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Webinar Series of the Chinese Antibody Society
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Wandong Zhang, Ph.D.
The blood-brain barrier (BBB) is a biological property of the brain microvessels and capillaries and plays a critical role in maintaining the physiological functions and homeostasis of central nervous system (CNS). BBB facilitates the passage of nutrients (such as amino acids, glucose, and nucleotides) into the CNS, exports metabolic wastes, …
Dr. Jian Tang
We are currently at the intersection of the AI and biology revolutions. On one hand, generative AI has made great breakthroughs recent years such as the ChatGPT, which is trained on a huge amount of text and code data and is able to have conversations with humans by generating very …
Dr. Li Peng
Immune checkpoint blockade has revolutionized cancer treatment. However, most patients encounter resistance not yet overcome by existing therapeutic approaches, urging the need for innovative therapies. Sialoglycans have emerged as a new dimension of immune checkpoints on various tumors that impair immune response. Cleaving off sialoglycans from tumors using a tumor-associated …
Dr. Weifeng Xu
Biotherapeutics such as mAbs are immunogenic hence can induce anti-drug Abs (ADA) including neutralizing ADA (NAb). These ADA/NAb can induce broad side-effects such as injection site overreaction, reduced exposure, to life-threatening endogenous counterpart neutralization and allergic response. Hence immunogenicity testing including ADA screening, confirmation and titer as well as NAb …