Therapeutic Antibodies: Bench to Market

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Nanobodies are typically obtained by immunizing camels or alpacas, and their animal-derived components have potential safety risks in clinical applications. In recent years, Dr. Ying’s team has developed the research and development platform for fully human nanobodies based on fully human germline genes. The team found that, due to their small size, and high stability and uniform properties, this kind of antibodies can be nebulized efficiently to form droplets with a median particle size of less than 5 microns, and the physical and chemical properties and biological activities of the antibodies will not be affected after nebulization. At the webinar, Dr. Ying will introduce the design, structure, property and function of this kind of antibody by taking anti-COVID-19 fully humanized nanobodies as an example.

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