Fundamentals of therapeutic antibody discovery
Time: Saturday, June 24, 2017 9m to 12 pm EDT (Sunday, June 25, 9 am to 10 am Beijing Time)
Abstract: In the past decades, biotherapeutics became an ever more important component of modern medicine. Currently, the majority of biotherapeutics on market and in the pipeline are monoclonal antibodies. Further, antibody and its fragments are building blocks for many innovative biotherapeutic modalities. This presentation will review the natural processes through which antibodies are engendered, and three major technology platforms to harness the useful antibodies with desired pharmacological properties. The talk will also discuss the principles for pharmaceutical considerations of therapeutic antibodies.
Speaker: Dr. Zhijian Lu
Dr. Zhijian Lu has a Bachelor’s degree in chemistry from Jilin University, China, in 1982，and a PhD degree in biochemistry from Boston University in 1991. He did his post-doctoral studies in Nobel laureate Dr. Gobind Khorana’s lab in MIT on structure-function relationship of rhodopsin. Dr. Lu started working at Genetics Institute/Wyeth/Pfizer 1993, where his researches were in the areas of cytokine structure/function studies, signal transduction/functional proteomics, and the discovery of biotherapeutics including recombinant proteins and monoclonal antibodies. He worked as the head of Novartis biologics discovery unit in Shanghai from 2011 to 2016. Currently Dr. Lu provides strategic and technical consultations to pharmaceutical and biotech companies.
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